24 U.S. AI Startups That Raised $100M+ in 2025: Interesting Startup Stories Redefining Success

U.S. AI startup


The U.S. AI startup ecosystem is setting new records in 2025. In just six months, 24 AI companies have raised over $100 million in funding—outpacing 2024 and reaffirming AI’s dominant role in the tech world. These successful business startups showcase what’s possible when innovation meets investment.

From billion-dollar rounds to breakthrough seed funding, each company has a unique story to tell. In January, ElevenLabs led the year with a $180M Series C, while Hippocratic AI secured $141M to revolutionize healthcare. By March, giants like OpenAI ($40B) and Anthropic ($3.5B) shook the industry. And in June, Anysphere raised a massive $900M, pushing its valuation to $10B.

These interesting startup stories reflect more than numbers—they highlight what it takes to scale in a competitive market. If you're wondering how to start your business in 2025, these AI startups are case studies in seizing the right moment with a bold vision.

At Jeffkom Story, we bring you the most compelling stories in tech and business. Stay inspired and follow us for more on funding trends, startup insights, and the future of innovation.

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